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Cholesterol is a fat-like material present in the blood and most tissues, especially nervous tissue. It is an important constituent of cell membranes, and various types of cholesterol are precursors of many steroid hormones and bile salts. Cholesterol is synthesized mainly in the liver. An elevated concentration of cholesterol in the blood is often associated with atheroma of which cholesterol is a major component. (Atheroma is the degeneration of the walls of the arteries due to the formation in them of fatty plaques and scar tissue.)
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